CaMKII tethers to L-type Ca(2+) channels, establishing a local and dedicated integrator of Ca(2+) signals for facilitation

Ca(2+)-dependent facilitation (CDF) of voltage-gated calcium current is a powerful mechanism for up-regulation of Ca(2+) influx during repeated membrane depolarization. CDF of L-type Ca(2+) channels (Ca(v)1.2) contributes to the positive force–frequency effect in the heart and is believed to involve...

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Detaylı Bibliyografya
Asıl Yazarlar: Hudmon, Andy, Schulman, Howard, Kim, James, Maltez, Janet M., Tsien, Richard W., Pitt, Geoffrey S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2005
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1343528/
https://ncbi.nlm.nih.gov/pubmed/16275756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200505155
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