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Alternative splicing modulates the frequency-dependent response of CaMKII to Ca(2+) oscillations
Ca(2+) oscillations are required in various signal trans duction pathways, and contain information both in their amplitude and frequency. Remarkably, the Ca(2+)/calmodulin(CaM)-dependent protein kinase II (CaMKII) can decode such frequencies. A Ca(2+)/CaM-stimulated autophosphorylation leads to Ca(2...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126106/ https://ncbi.nlm.nih.gov/pubmed/12110572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf360 |
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