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Alternative splicing modulates the frequency-dependent response of CaMKII to Ca(2+) oscillations

Ca(2+) oscillations are required in various signal trans duction pathways, and contain information both in their amplitude and frequency. Remarkably, the Ca(2+)/calmodulin(CaM)-dependent protein kinase II (CaMKII) can decode such frequencies. A Ca(2+)/CaM-stimulated autophosphorylation leads to Ca(2...

詳細記述

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書誌詳細
主要な著者: Bayer, K.Ulrich, De Koninck, Paul, Schulman, Howard
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC126106/
https://ncbi.nlm.nih.gov/pubmed/12110572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf360
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