Counting CAG repeats in the Huntington’s disease gene by restriction endonuclease EcoP15I cleavage

Huntington’s disease (HD) is a progressive neurodegenerative disorder with autosomal-dominant inheritance. The disease is caused by a CAG trinucleotide repeat expansion located in the first exon of the HD gene. The CAG repeat is highly polymorphic and varies from 6 to 37 repeats on chromosomes of un...

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Bibliografiska uppgifter

I publikationen:	Nucleic Acids Res
Huvudupphov:	Möncke-Buchner, Elisabeth, Reich, Stefanie, Mücke, Merlind, Reuter, Monika, Messer, Walter, Wanker, Erich E., Krüger, Detlev H.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Oxford University Press 2002
Ämnen:	NAR Methods Online
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134256/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12177311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf082
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