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Counting CAG repeats in the Huntington’s disease gene by restriction endonuclease EcoP15I cleavage

Huntington’s disease (HD) is a progressive neurodegenerative disorder with autosomal-dominant inheritance. The disease is caused by a CAG trinucleotide repeat expansion located in the first exon of the HD gene. The CAG repeat is highly polymorphic and varies from 6 to 37 repeats on chromosomes of un...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Möncke-Buchner, Elisabeth, Reich, Stefanie, Mücke, Merlind, Reuter, Monika, Messer, Walter, Wanker, Erich E., Krüger, Detlev H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2002
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC134256/
https://ncbi.nlm.nih.gov/pubmed/12177311
Tagiau: Ychwanegu Tag
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