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EcoRII: a restriction enzyme evolving recombination functions?
The restriction endonuclease EcoRII requires the cooperative interaction with two copies of the sequence 5′CCWGG for DNA cleavage. We found by limited proteolysis that EcoRII has a two-domain structure that enables this particular mode of protein–DNA interaction. The C-terminal domain is a new restr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129036/ https://ncbi.nlm.nih.gov/pubmed/12356742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf514 |
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