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EcoRII: a restriction enzyme evolving recombination functions?

The restriction endonuclease EcoRII requires the cooperative interaction with two copies of the sequence 5′CCWGG for DNA cleavage. We found by limited proteolysis that EcoRII has a two-domain structure that enables this particular mode of protein–DNA interaction. The C-terminal domain is a new restr...

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Autori principali: Mücke, Merlind, Grelle, Gerlinde, Behlke, Joachim, Kraft, Regine, Krüger, Detlev H., Reuter, Monika
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC129036/
https://ncbi.nlm.nih.gov/pubmed/12356742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf514
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