EcoRII: a restriction enzyme evolving recombination functions?

The restriction endonuclease EcoRII requires the cooperative interaction with two copies of the sequence 5′CCWGG for DNA cleavage. We found by limited proteolysis that EcoRII has a two-domain structure that enables this particular mode of protein–DNA interaction. The C-terminal domain is a new restr...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Mücke, Merlind, Grelle, Gerlinde, Behlke, Joachim, Kraft, Regine, Krüger, Detlev H., Reuter, Monika
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2002
Fag:	Articles
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129036/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12356742/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf514
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