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EcoRII: a restriction enzyme evolving recombination functions?

The restriction endonuclease EcoRII requires the cooperative interaction with two copies of the sequence 5′CCWGG for DNA cleavage. We found by limited proteolysis that EcoRII has a two-domain structure that enables this particular mode of protein–DNA interaction. The C-terminal domain is a new restr...

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Bibliografische gegevens
Hoofdauteurs: Mücke, Merlind, Grelle, Gerlinde, Behlke, Joachim, Kraft, Regine, Krüger, Detlev H., Reuter, Monika
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC129036/
https://ncbi.nlm.nih.gov/pubmed/12356742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf514
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