RhoGEF Specificity Mutants Implicate RhoA as a Target for Dbs Transforming Activity

Dbs is a Rho-specific guanine nucleotide exchange factor (RhoGEF) that exhibits transforming activity when overexpressed in NIH 3T3 mouse fibroblasts. Like many RhoGEFs, the in vitro catalytic activity of Dbs is not limited to a single substrate. It can catalyze the exchange of GDP for GTP on RhoA a...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Cheng, Li, Rossman, Kent L., Mahon, Gwendolyn M., Worthylake, David K., Korus, Malgorzata, Sondek, John, Whitehead, Ian P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Cell Growth and Development
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC134030/
https://ncbi.nlm.nih.gov/pubmed/12215546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6895-6905.2002
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares