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RhoGEF Specificity Mutants Implicate RhoA as a Target for Dbs Transforming Activity
Dbs is a Rho-specific guanine nucleotide exchange factor (RhoGEF) that exhibits transforming activity when overexpressed in NIH 3T3 mouse fibroblasts. Like many RhoGEFs, the in vitro catalytic activity of Dbs is not limited to a single substrate. It can catalyze the exchange of GDP for GTP on RhoA a...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC134030/ https://ncbi.nlm.nih.gov/pubmed/12215546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.19.6895-6905.2002 |
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