RhoGEF Specificity Mutants Implicate RhoA as a Target for Dbs Transforming Activity

Dbs is a Rho-specific guanine nucleotide exchange factor (RhoGEF) that exhibits transforming activity when overexpressed in NIH 3T3 mouse fibroblasts. Like many RhoGEFs, the in vitro catalytic activity of Dbs is not limited to a single substrate. It can catalyze the exchange of GDP for GTP on RhoA a...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Cheng, Li, Rossman, Kent L., Mahon, Gwendolyn M., Worthylake, David K., Korus, Malgorzata, Sondek, John, Whitehead, Ian P.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2002
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134030/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12215546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.19.6895-6905.2002
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