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RhoGEF Specificity Mutants Implicate RhoA as a Target for Dbs Transforming Activity

Dbs is a Rho-specific guanine nucleotide exchange factor (RhoGEF) that exhibits transforming activity when overexpressed in NIH 3T3 mouse fibroblasts. Like many RhoGEFs, the in vitro catalytic activity of Dbs is not limited to a single substrate. It can catalyze the exchange of GDP for GTP on RhoA a...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell Biol
Asıl Yazarlar: Cheng, Li, Rossman, Kent L., Mahon, Gwendolyn M., Worthylake, David K., Korus, Malgorzata, Sondek, John, Whitehead, Ian P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2002
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC134030/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12215546/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.19.6895-6905.2002
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