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Interactions between Telomerase and Primase Physically Link the Telomere and Chromosome Replication Machinery
In the ciliate Euplotes crassus, millions of new telomeres are synthesized by telomerase and polymerase α-primase during macronuclear development in mated cells. Concomitant with de novo telomere formation, telomerase assembles into higher-order complexes of 550 kDa, 1,600 kDa, and 5 MDa. We show he...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133977/ https://ncbi.nlm.nih.gov/pubmed/12138196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.16.5859-5868.2002 |
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