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Mutations in DNA Replication Genes Reduce Yeast Life Span

Surprisingly, the contribution of defects in DNA replication to the determination of yeast life span has never been directly investigated. We show that a replicative yeast helicase/nuclease, encoded by DNA2 and a member of the same helicase subfamily as the RecQ helicases, is required for normal lif...

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Detalhes bibliográficos
Main Authors: Mays Hoopes, Laura L., Budd, Martin, Choe, Wonchae, Weitao, Tao, Campbell, Judith L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133874/
https://ncbi.nlm.nih.gov/pubmed/12024027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4136-4146.2002
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