Mutations in DNA Replication Genes Reduce Yeast Life Span

Surprisingly, the contribution of defects in DNA replication to the determination of yeast life span has never been directly investigated. We show that a replicative yeast helicase/nuclease, encoded by DNA2 and a member of the same helicase subfamily as the RecQ helicases, is required for normal lif...

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Bibliographische Detailangaben
Hauptverfasser: Mays Hoopes, Laura L., Budd, Martin, Choe, Wonchae, Weitao, Tao, Campbell, Judith L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
DNA Dynamics and Chromosome Structure
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133874/
https://ncbi.nlm.nih.gov/pubmed/12024027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.12.4136-4146.2002
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