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Hsp72 and Stress Kinase c-jun N-Terminal Kinase Regulate the Bid-Dependent Pathway in Tumor Necrosis Factor-Induced Apoptosis

The major inducible heat shock protein Hsp72 has been shown to protect cells from certain apoptotic stimuli. Here we investigated the mechanism of Hsp72-mediated protection from tumor necrosis factor (TNF)-induced apoptosis of primary culture of IMR90 human fibroblasts. Hsp72 temporarily blocked apo...

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Détails bibliographiques
Auteurs principaux: Gabai, Vladimir L., Mabuchi, Katsuhide, Mosser, Dick D., Sherman, Michael Y.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC133785/
https://ncbi.nlm.nih.gov/pubmed/11971973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.10.3415-3424.2002
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