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Hsp72 and Stress Kinase c-jun N-Terminal Kinase Regulate the Bid-Dependent Pathway in Tumor Necrosis Factor-Induced Apoptosis

The major inducible heat shock protein Hsp72 has been shown to protect cells from certain apoptotic stimuli. Here we investigated the mechanism of Hsp72-mediated protection from tumor necrosis factor (TNF)-induced apoptosis of primary culture of IMR90 human fibroblasts. Hsp72 temporarily blocked apo...

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Udgivet i:Mol Cell Biol
Principais autores: Gabai, Vladimir L., Mabuchi, Katsuhide, Mosser, Dick D., Sherman, Michael Y.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2002
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133785/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11971973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.10.3415-3424.2002
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