Central Role for the XRCC1 BRCT I Domain in Mammalian DNA Single-Strand Break Repair

The DNA single-strand break repair (SSBR) protein XRCC1 is required for genetic stability and for embryonic viability. XRCC1 possesses two BRCA1 carboxyl-terminal (BRCT) protein interaction domains, denoted BRCT I and II. BRCT II is required for SSBR during G(1) but is dispensable for this process d...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Mol Cell Biol
Prif Awduron:	Taylor, Richard M., Thistlethwaite, Angela, Caldecott, Keith W.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Taylor & Francis 2002
Pynciau:	DNA Dynamics and Chromosome Structure
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11909950/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.8.2556-2563.2002
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