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Central Role for the XRCC1 BRCT I Domain in Mammalian DNA Single-Strand Break Repair
The DNA single-strand break repair (SSBR) protein XRCC1 is required for genetic stability and for embryonic viability. XRCC1 possesses two BRCA1 carboxyl-terminal (BRCT) protein interaction domains, denoted BRCT I and II. BRCT II is required for SSBR during G(1) but is dispensable for this process d...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC133733/ https://ncbi.nlm.nih.gov/pubmed/11909950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.8.2556-2563.2002 |
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