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Akt/Protein Kinase B Promotes Organ Growth in Transgenic Mice

One of the least-understood areas in biology is the determination of the size of animals and their organs. In Drosophila, components of the insulin receptor phosphoinositide 3-kinase (PI3K) pathway determine body, organ, and cell size. Several biochemical studies have suggested that Akt/protein kina...

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Pubblicato in:Mol Cell Biol
Autori principali: Shioi, Tetsuo, McMullen, Julie R., Kang, Peter M., Douglas, Pamela S., Obata, Toshiyuki, Franke, Thomas F., Cantley, Lewis C., Izumo, Seigo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2002
Soggetti:
Cell Growth and Development
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133704/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11909972/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.8.2799-2809.2002
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