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Murine De Novo Methyltransferase Dnmt3a Demonstrates Strand Asymmetry and Site Preference in the Methylation of DNA In Vitro

CpG methylation is involved in a wide range of biological processes in vertebrates as well as in plants and fungi. To date, three enzymes, Dnmt1, Dnmt3a, and Dnmt3b, are known to have DNA methyltransferase activity in mouse and human. It has been proposed that de novo methylation observed in early e...

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Publicado en:Mol Cell Biol
Autores principales: Lin, Iping G., Han, Li, Taghva, Alexander, O’Brien, Laura E., Hsieh, Chih-Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2002
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133553/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11784849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.3.704-723.2002
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