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Murine De Novo Methyltransferase Dnmt3a Demonstrates Strand Asymmetry and Site Preference in the Methylation of DNA In Vitro

CpG methylation is involved in a wide range of biological processes in vertebrates as well as in plants and fungi. To date, three enzymes, Dnmt1, Dnmt3a, and Dnmt3b, are known to have DNA methyltransferase activity in mouse and human. It has been proposed that de novo methylation observed in early e...

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Bibliografske podrobnosti
Main Authors: Lin, Iping G., Han, Li, Taghva, Alexander, O’Brien, Laura E., Hsieh, Chih-Lin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC133553/
https://ncbi.nlm.nih.gov/pubmed/11784849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.3.704-723.2002
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