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Molecular Balance between the Regulatory and Catalytic Subunits of Phosphoinositide 3-Kinase Regulates Cell Signaling and Survival

Class Ia phosphoinositide (PI) 3-kinase is a central component in growth factor signaling and is comprised of a p110 catalytic subunit and a regulatory subunit, the most common family of which is derived from the p85α gene (Pik3r1). Optimal signaling through the PI 3-kinase pathway depends on a crit...

詳細記述

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書誌詳細
出版年:Mol Cell Biol
主要な著者: Ueki, Kohjiro, Fruman, David A., Brachmann, Saskia M., Tseng, Yu-Hua, Cantley, Lewis C., Kahn, C. Ronald
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133541/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11784871/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.3.965-977.2002
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