XRCC1 is phosphorylated by DNA-dependent protein kinase in response to DNA damage

The two BRCT domains (BRCT1 and BRCT2) of XRCC1 mediate a network of protein–protein interactions with several key factors of the DNA single-strand breaks (SSBs) and base damage repair pathways. BRCT1 is required for the immediate poly(ADP–ribose)-dependent recruitment of XRCC1 to DNA breaks and is...

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Autori principali: Lévy, Nicolas, Martz, Adeline, Bresson, Anne, Spenlehauer, Catherine, de Murcia, Gilbert, Ménissier-de Murcia, Josiane
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1325201/
https://ncbi.nlm.nih.gov/pubmed/16397295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj409
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