XRCC1 interacts with the p58 subunit of DNA Pol α-primase and may coordinate DNA repair and replication during S phase

Repair of single-stranded DNA breaks before DNA replication is critical in maintaining genomic stability; however, how cells deal with these lesions during S phase is not clear. Using combined approaches of proteomics and in vitro and in vivo protein–protein interaction, we identified the p58 subuni...

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Détails bibliographiques
Auteurs principaux: Lévy, Nicolas, Oehlmann, Maren, Delalande, François, Nasheuer, Heinz Peter, Van Dorsselaer, Alain, Schreiber, Valérie, de Murcia, Gilbert, Ménissier-de Murcia, Josiane, Maiorano, Domenico, Bresson, Anne
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2009
Sujets:
Genome Integrity, Repair and Replication
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691816/
https://ncbi.nlm.nih.gov/pubmed/19305001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp144
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