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Perforin-dependent elimination of dendritic cells regulates the expansion of antigen-specific CD8(+) T cells in vivo
The lifespan and survival of dendritic cells (DC) in vivo are potentially critical to the expansion of T cell immune responses. We have previously reported that DC loaded with specific antigen are rapidly eliminated by cytotoxic T lymphocytes (CTL) in vivo, but the site, mechanism, and consequences...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1324995/ https://ncbi.nlm.nih.gov/pubmed/16373503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509054103 |
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