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Monocyte-Derived Dendritic Cells Are Essential for CD8(+) T Cell Activation and Antitumor Responses After Local Immunotherapy

Tumors harbor several populations of dendritic cells (DCs) with the ability to prime tumor-specific T cells. However, these T cells mostly fail to differentiate into armed effectors and are unable to control tumor growth. We have previously shown that treatment with immunostimulatory agents at the t...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Kuhn, Sabine, Yang, Jianping, Ronchese, Franca
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655312/
https://ncbi.nlm.nih.gov/pubmed/26635798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00584
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