Inefficient boosting of antitumor CD8(+) T cells by dendritic-cell vaccines is rescued by restricting T-cell cytotoxic functions

Dendritic cells (DCs) are powerful activators of primary and secondary immune responses and have promising activity as anticancer vaccines. However, various populations of immune cells, including natural killer cells, regulatory T cells and especially cytotoxic T lymphocytes (CTLs), can inhibit DC f...

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Bibliografski detalji
Glavni autori: Zhi-Iong Ma, Joel, Yang, Jianping, Qin, Jim S., Richter, Antonia, Perret, Rachel, El-Deiry, Wafik S., Finnberg, Niklas, ronchese, franca
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2012
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525606/
https://ncbi.nlm.nih.gov/pubmed/23264897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22128
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