Inefficient boosting of antitumor CD8(+) T cells by dendritic-cell vaccines is rescued by restricting T-cell cytotoxic functions

Dendritic cells (DCs) are powerful activators of primary and secondary immune responses and have promising activity as anticancer vaccines. However, various populations of immune cells, including natural killer cells, regulatory T cells and especially cytotoxic T lymphocytes (CTLs), can inhibit DC f...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zhi-Iong Ma, Joel, Yang, Jianping, Qin, Jim S., Richter, Antonia, Perret, Rachel, El-Deiry, Wafik S., Finnberg, Niklas, ronchese, franca
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Landes Bioscience 2012
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525606/
https://ncbi.nlm.nih.gov/pubmed/23264897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.22128
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