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Expression of a homodimeric type I cytokine receptor is required for JAK2V617F-mediated transformation
A recurrent somatic activating mutation in the nonreceptor tyrosine kinase JAK2 (JAK2V617F) occurs in the majority of patients with the myeloproliferative disorders polycythemia vera, essential thrombocythemia, myelofibrosis with myeloid metaplasia, and, less commonly, chronic myelomonocytic leukemi...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1323216/ https://ncbi.nlm.nih.gov/pubmed/16365288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0509714102 |
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