Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice

Little is known about the overall patterns of thyroid hormone (Th)-mediated gene regulation by the main Th receptor (Tr) isoforms, Tr-α and Tr-β, in vivo. We used 48 complementary DNA microarrays to examine hepatic gene expression profiles of wild-type and Thra and Thrb knockout mice under different...

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Main Authors: Yen, Paul M., Feng, Xu, Flamant, Frederic, Chen, Yidong, Walker, Robert L., Weiss, Roy E., Chassande, Olivier, Samarut, Jacques, Refetoff, Samuel, Meltzer, Paul S.
格式: Artigo
語言:Inglês
出版: 2003
主題:
Scientific Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1319202/
https://ncbi.nlm.nih.gov/pubmed/12776178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor862
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