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Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors

Thyroid hormone (3,5,3′-triiodo-l-thyronine or T3) exerts a pleiotropic activity during central nervous system development. Hypothyroidism during the fetal and postnatal life results in an irreversible mental retardation syndrome. At the cellular level, T3 is known to act on neuronal and glial linea...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Baas, Dominique, Legrand, Claude, Samarut, Jacques, Flamant, Frédéric
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2002
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052482299
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