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Persistence of oligodendrocyte precursor cells and altered myelination in optic nerve associated to retina degeneration in mice devoid of all thyroid hormone receptors

Thyroid hormone (3,5,3′-triiodo-l-thyronine or T3) exerts a pleiotropic activity during central nervous system development. Hypothyroidism during the fetal and postnatal life results in an irreversible mental retardation syndrome. At the cellular level, T3 is known to act on neuronal and glial linea...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Baas, Dominique, Legrand, Claude, Samarut, Jacques, Flamant, Frédéric
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2002
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.052482299
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