Genetic Analysis Reveals Different Functions for the Products of the Thyroid Hormone Receptor α Locus

Thyroid hormone receptors are encoded by the TRα (NR1A1) and TRβ (NR1A2) loci. These genes are transcribed into multiple variants whose functions are unclear. Analysis by gene inactivation in mice has provided new insights into the functional complexity of these products. Different strategies design...

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Autors principals: Gauthier, Karine, Plateroti, Michelina, Harvey, Clare B., Williams, Graham R., Weiss, Roy E., Refetoff, Samuel, Willott, James F., Sundin, Victoria, Roux, Jean-Paul, Malaval, Luc, Hara, Masahiro, Samarut, Jacques, Chassande, Olivier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC87157/
https://ncbi.nlm.nih.gov/pubmed/11416150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4748-4760.2001
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