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Stereostructure of luminamicin, an anaerobic antibiotic, via molecular dynamics, NMR spectroscopy, and the modified Mosher method

The absolute stereostructure of luminamicin, an anaerobic antibiotic, has been determined by using conformational analysis via high-temperature molecular dynamics, NMR spectroscopy, and the modified Mosher method. It was found that luminamicin has the S, S, R, R, R, R, S, S, S, R, and S configuratio...

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Detalhes bibliográficos
Main Authors: Gouda, Hiroaki, Sunazuka, Toshiaki, Ui, Hideaki, Handa, Masaki, Sakoh, Yusuke, Iwai, Yuzuru, Hirono, Shuichi, Ōmura, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317948/
https://ncbi.nlm.nih.gov/pubmed/16344486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508425102
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