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Absolute Configuration Determination of Retroflexanone Using the Advanced Mosher Method and Application of HPLC-NMR

The absolute configuration of retroflexanone (1) and a closely related phlorogluinol (2) was established using the advanced Mosher method and by application of HPLC-NMR. HPLC-NMR permitted a small scale Mosher method analysis to be carried out on these unstable phloroglucinols.

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Singleton, Caleb, Brkljača, Robert, Urban, Sylvia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025468/
https://ncbi.nlm.nih.gov/pubmed/29895761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16060205
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