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Total Synthesis of Gobiusxanthin Stereoisomers and Their Application to Determination of Absolute Configurations of Natural Products: Revision of Reported Absolute Configuration of Epigobiusxanthin

(3R)-Gobiusxanthin stereoisomers (1a–d) were synthesized by stereoselective Wittig reaction of the (3R)-C(15)-acetylenic tri-n-butylphosphonium salt 7 with C(25)-apocarotenal stereoisomers 5a,b and 14a,b bearing four kinds of 3,6-dihydroxy-ε-end groups. The validity of the reported stereochemistry o...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Yamano, Yumiko, Ematsu, Kotaro, Kurimoto, Hiromasa, Maoka, Takashi, Wada, Akimori
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306930/
https://ncbi.nlm.nih.gov/pubmed/25561412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13010159
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