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Total synthesis and determination of the absolute configuration of a natural analgesic: crotonine
We report the first total synthesis of four possible absolute configurations and four other regional isomers of a naturally occurring alkaloid crotonine, which was isolated from Croton tiglium L. (Euphoriaceae) without elucidation of its absolute configuration. The concise five-step route with a chi...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131603/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13659-013-0080-1 |
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