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The corticotropin-releasing factor receptor-1 pathway mediates the negative affective states of opiate withdrawal
The negative affective symptoms of opiate withdrawal powerfully motivate drug-seeking behavior and may trigger relapse to heroin abuse. To date, no medications exist that effectively relieve the negative affective symptoms of opiate withdrawal. The corticotropin-releasing factor (CRF) system has bee...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317931/ https://ncbi.nlm.nih.gov/pubmed/16339307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506999102 |
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