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Disruption of the CRF(2) Receptor Pathway Decreases the Somatic Expression of Opiate Withdrawal
Escape from the extremely aversive opiate withdrawal symptoms powerfully motivates compulsive drug-seeking and drug-taking behaviors. The corticotropin-releasing factor (CRF) system is hypothesized to mediate the motivational properties of drug dependence. CRF signaling is transmitted by two recepto...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760329/ https://ncbi.nlm.nih.gov/pubmed/18288089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.8 |
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