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Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats

Tobacco addiction is a chronic disorder that is characterized by a negative affective state upon smoking cessation and relapse after periods of abstinence. Previous research has shown that an increased central release of corticotropin-releasing factor (CRF) at least partly mediates the deficit in br...

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Bibliografiske detaljer
Main Authors: Marcinkiewcz, Catherine A., Prado, Melissa M., Isaac, Shani K., Marshall, Alex, Rylkova, Daria, Bruijnzeel, Adrie W.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680924/
https://ncbi.nlm.nih.gov/pubmed/19145226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2008.231
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