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Crystal structure of wild-type human thrombin in the Na(+)-free state
Regulation of thrombin activity is critical for haemostasis and the prevention of thrombosis. Thrombin has several procoagulant substrates, including fibrinogen and platelet receptors, and essential cofactors for stimulating its own formation. However, thrombin is also capable of serving an anticoag...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1317660/ https://ncbi.nlm.nih.gov/pubmed/16201969 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051217 |
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