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Crystal structure of wild-type human thrombin in the Na(+)-free state

Regulation of thrombin activity is critical for haemostasis and the prevention of thrombosis. Thrombin has several procoagulant substrates, including fibrinogen and platelet receptors, and essential cofactors for stimulating its own formation. However, thrombin is also capable of serving an anticoag...

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Autors principals: Johnson, Daniel J. D., Adams, Ty E., Li, Wei, Huntington, James A.
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317660/
https://ncbi.nlm.nih.gov/pubmed/16201969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051217
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