Activation of TRAP/Mediator Subunit TRAP220/Med1 Is Regulated by Mitogen-Activated Protein Kinase-Dependent Phosphorylation

The TRAP/Mediator coactivator complex serves as a molecular bridge between gene-specific activators and RNA polymerase II. TRAP220/Med1 is a key component of TRAP/Mediator that targets the complex to nuclear hormone receptors and other types of activators. We show here that human TRAP220/Med1 is a s...

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Bibliografiske detaljer
Main Authors: Pandey, Pradeep K., Udayakumar, T. S., Lin, Xinjie, Sharma, Dipali, Shapiro, Paul S., Fondell, Joseph D.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316958/
https://ncbi.nlm.nih.gov/pubmed/16314496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.24.10695-10710.2005
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