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MED1 Phosphorylation Promotes Its Association with Mediator: Implications for Nuclear Receptor Signaling

Mediator is a conserved multisubunit complex that acts as a functional interface between regulatory transcription factors and the general RNA polymerase II initiation apparatus. MED1 is a pivotal component of the complex that binds to nuclear receptors and a broad array of other gene-specific activa...

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Bibliographic Details
Main Authors: Belakavadi, Madesh, Pandey, Pradeep K., Vijayvargia, Ravi, Fondell, Joseph D.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423130/
https://ncbi.nlm.nih.gov/pubmed/18391015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02191-07
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