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Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase α (CCTα)
Farnesol (FOH) inhibits the CDP-choline pathway for PtdCho (phosphatidylcholine) synthesis, an activity that is involved in subsequent induction of apoptosis. Interestingly, the rate-limiting enzyme in this pathway, CCTα (CTP:phosphocholine cytidylyltransferase α), is rapidly activated, cleaved by c...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1316283/ https://ncbi.nlm.nih.gov/pubmed/16097951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051021 |
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