Caspase Processing and Nuclear Export of CTP:Phosphocholine Cytidylyltransferase α during Farnesol-Induced Apoptosis

CTP:phosphocholine cytidylyltransferase alpha (CCTα) is a nuclear enzyme that catalyzes the rate-limiting step in the CDP-choline pathway, the primary route for synthesis of phosphatidylcholine (PtdCho) in eukaryotic cells. Induction of apoptosis by farnesol (FOH) and other cytotoxic drugs has been...

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Detalhes bibliográficos
Main Authors: Lagace, Thomas A., Miller, Jessica R., Ridgway, Neale D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133913/
https://ncbi.nlm.nih.gov/pubmed/12052891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4851-4862.2002
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