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Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase α (CCTα)

Farnesol (FOH) inhibits the CDP-choline pathway for PtdCho (phosphatidylcholine) synthesis, an activity that is involved in subsequent induction of apoptosis. Interestingly, the rate-limiting enzyme in this pathway, CCTα (CTP:phosphocholine cytidylyltransferase α), is rapidly activated, cleaved by c...

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Bibliografski detalji
Glavni autori: Lagace, Thomas A., Ridgway, Neale D.
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1316283/
https://ncbi.nlm.nih.gov/pubmed/16097951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051021
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