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Multiple roles for kinases in DNA replication

DNA replication is carried out by the replisome, which includes several proteins that are targets of cell-cycle-regulated kinases. The phosphorylation of proteins such as replication protein A, DNA polymerase-α and -δ, replication factor C, flap endonuclease 1 and DNA ligase I leads to their inactiv...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Henneke, Ghislaine, Koundrioukoff, Stéphane, Hübscher, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315902/
https://ncbi.nlm.nih.gov/pubmed/12634841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor774
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