A carregar...
The flexible loop of human FEN1 endonuclease is required for flap cleavage during DNA replication and repair
The conserved, structure-specific flap endonuclease FEN1 cleaves 5′ DNA flaps that arise during replication or repair. To address in vivo mechanisms of flap cleavage, we developed a screen for human FEN1 mutants that are toxic when expressed in yeast. Two targets were revealed: the flexible loop dom...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC131084/ https://ncbi.nlm.nih.gov/pubmed/12411510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf587 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|