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Dynamics of the interaction between the insulin receptor and protein tyrosine-phosphatase 1B in living cells

The dynamics of the interaction of the insulin receptor with a substrate-trapping mutant of protein-tyrosine phosphatase 1B (PTP1B) were monitored in living human embryonic kidney cells using bioluminescence resonance energy transfer (BRET). Insulin dose-dependently stimulates this interaction, whic...

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Detalhes bibliográficos
Main Authors: Boute, Nicolas, Boubekeur, Samira, Lacasa, Danièle, Issad, Tarik
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315895/
https://ncbi.nlm.nih.gov/pubmed/12634852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.embor767
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