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Interaction of Constitutive Photomorphogenesis 1 Protein with Protein-Tyrosine Phosphatase 1B Suppresses Protein-Tyrosine Phosphatase 1B Activity and Enhances Insulin Signaling

Recent studies reveal that COP1 suppresses the expression of gluconeogenetic genes and prohibits hepatic glucose production. To get more insight into COP1 in hepatic cells, we examined the impact of COP1 on insulin-responsive genes and insulin signaling. We found that COP1 increased the responsivene...

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Detalhes bibliográficos
Main Authors: Ren, Wenying, Sun, Yingmin, Cheema, Sarwat, Du, Keyong
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624470/
https://ncbi.nlm.nih.gov/pubmed/23439647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.369371
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